PEG-400

PEG-400 (Polyethylene Glycol 400) Research Standard

PEG-400 (Polyethylene Glycol 400) is a versatile, low-molecular-weight polyether polymer characterized by its repeating ethylene glycol units. As a laboratory-grade liquid, it functions as a critical reagent in chemical research due to its amphiphilic nature—possessing both hydrophilic oxyethylene units and a hydrophobic backbone. This unique property allows PEG-400 to act as a universal solvent, plasticizer, and humectant in controlled in vitro formulation studies and polymer synthesis. It is supplied for professional laboratory use to facilitate the stabilization and solubilization of complex chemical compounds.

Technical Specifications

Mechanism of Action & Research Context

PEG-400 is highly valued in research for its ability to mediate interactions between solutes and solvent environments, primarily driven by its structural characteristics.

• Solubilization: The oxyethylene units in the polymer chain are highly effective at forming hydrogen bonds with water, while the overall structure maintains regions of hydrophobic character. This dual functionality enables the polymer to dissolve both polar and non-polar compounds, making it an essential solvent for poorly soluble substances in experimental batches.

• Chemical Reactivity: The presence of terminal hydroxyl groups (-OH) provides sites for further chemical modification. Researchers often utilize these terminal groups to create block copolymers or to graft PEG-400 onto other molecular scaffolds.

• Humectant Properties: Due to its molecular weight and hygroscopic nature, PEG-400 is effectively used to control the humidity and hydration levels of chemical systems in analytical research.

Research Applications

PEG-400 serves as a foundational reagent for chemical formulation and analytical studies.

Primary fields of in vitro laboratory investigation include:

• Solvent & Delivery Systems: Serving as a primary vehicle to dissolve hydrophobic compounds for downstream biological or chemical testing.

• Polymer Synthesis: Utilizing the polymer chain as a precursor in the creation of block copolymers or dendrimers for material science research.

• Plasticizer Studies: Investigating the modification of the mechanical and physical properties of research-grade films or matrices.

• Crystallization Research: Acting as a medium to control the rate of crystal formation and nucleation in controlled solution studies.

Storage & Handling Guidelines

To maintain the chemical stability and experimental viability of the polymer:

• Moisture Management: The material is hygroscopic; ensure containers are sealed tightly at all times to prevent moisture absorption from the atmosphere.

• Thermal Environment: Store at controlled ambient temperatures. Avoid exposure to extreme heat or freezing conditions, as these can affect the viscosity and consistency of the polymer.

• Light Protection: Store in original opaque containers (amber glass or high-density plastic) to prevent light-induced degradation.

• Quality Inspection: Before use, inspect the liquid for clarity. Discard the batch if discoloration, turbidity, or signs of precipitation are observed.

Research Use Disclaimer

Research Use Only Disclaimer: This product is developed and distributed strictly as a Research Use Only (RUO) laboratory reference chemical intended exclusively for non-clinical analytical and scientific investigation. It is not an FDA-approved drug, medical treatment, dietary supplement, or food ingredient, and is strictly prohibited for human or animal consumption. Kimera Chems supplies this high-purity research material solely to qualified institutions and professional investigators for authorized laboratory research.