SM04554 (Dalosirvat) Research Standard
SM04554, also known as Dalosirvat, is a synthetic research compound characterized by a distinctive 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-phenylbutane-1,4-dione structure. Featuring a diketone functional group and a benzodioxin ring system, this molecule is designed to probe specific cellular signaling pathways. In laboratory research, SM04554 is utilized in cell-based assays and molecular binding experiments to map protein-ligand interactions and evaluate the kinetics of molecular binding in controlled in vitro environments.
Technical Specifications
| Property | Specification |
| Product Name | SM04554 (Dalosirvat) |
| IUPAC Name | 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-phenylbutane-1,4-dione |
| Chemical Formula | C₁₈H₁₆O₄ |
| Molecular Weight | 296.3 g/mol |
| Physical Appearance | Light yellow to yellow |
| Concentration | 2.5 mg/mL (Solution) |
| Assay Purity | ≥ 98% (HPLC verified) |
Mechanism of Action & Research Context
SM04554 is primarily investigated for its unique structural arrangement, which enables targeted protein-ligand interactions.
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Diketone Framework: The molecule features two ketone groups within a butanedione-like framework. One ketone is attached to a phenyl ring, while the second is integrated with a benzodioxin ring system. This specific configuration is hypothesized to facilitate interaction with protein binding sites.
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Binding Dynamics: The three-dimensional conformation of the benzodioxin and phenyl components provides the basis for binding studies, where researchers examine how the molecule interacts with cellular signaling proteins.
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Pathway Modulation: By influencing these specific binding sites, the compound serves as a tool for studying the modulation of signaling pathways in controlled in vitro environments.
Research Applications
SM04554 is a specialized reagent essential for biochemical and structural research.
Primary fields of in vitro laboratory investigation include:
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Protein-Ligand Interaction Kinetics: Measuring the binding affinity and dissociation rates between SM04554 and target protein receptors.
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Molecular Conformation Analysis: Examining the structure of the compound in solution to understand the orientation of the diketone and benzodioxin moieties.
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Stability & Solubility Profiling: Monitoring the compound’s chemical degradation and dissolution profiles across various solvent systems to refine laboratory protocols.
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Cell-Based Signaling Assays: Using the compound to probe the response of cellular systems to exogenous signaling modulation.
Storage & Handling Guidelines
To maintain the chemical stability and experimental reliability of the solution:
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Container Integrity: Keep in the original container. Ensure the lid is closed tightly after every use to prevent solvent evaporation.
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Integrity Check: The material must be discarded properly if any signs of precipitation or discoloration occur, as this may indicate degradation or compromised stability.
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Handling Hygiene: Utilize sterile, non-reactive laboratory equipment to draw samples and prevent cross-contamination.
Research Use Disclaimer
Research Use Only Disclaimer: This product is developed and distributed strictly as a Research Use Only (RUO) laboratory reference chemical intended exclusively for non-clinical analytical and scientific investigation. It is not an FDA-approved drug, medical treatment, dietary supplement, or food ingredient, and is strictly prohibited for human or animal consumption. Kimera Chems supplies this high-purity research material solely to qualified institutions and professional investigators for authorized laboratory research.
| CAS Number | 1360540-81-3 |
| Other Names | Dalosirvat, QX6T87A52I, SM-04554 |
| IUPAC Name | 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-phenylbutane-1,4-dione |
| Molecular Formula | C₁₈H₁₆O₄ |
| Molecular Weight | 296.3 |
| Liquid Concentration And Solution | 2.5mg/ml DMI, 1,3 Propanediol, Glycerin, Ethanol, Deionized Water |


