ACE-031 (Myostatin Inhibitory Peptide 7)

  Identity A synthetic 24-residue peptide corresponding to the myostatin-binding region derived from activin receptor type IIB, C-terminally amidated. It functions in research as a myostatin (GDF-8) ligand-binding peptide.

Note on nomenclature: This is the ActRIIB-derived myostatin-binding peptide. The name “ACE-031” is also historically associated with a larger recombinant ActRIIB-Fc fusion protein; the material supplied here is the 24-residue synthetic peptide identified by CAS 1621169-52-5, confirmed by sequence and mass. Reported activity Myostatin Inhibitory Peptide 7 is studied as a myostatin (GDF-8) ligand-binding peptide, derived from the activin receptor type IIB binding region. Published research contexts include:

• Myostatin/GDF-8 binding studies — SPR and competitive binding assays characterizing affinity and kinetics against ActRIIB
• TGF-β superfamily signaling — SMAD pathway modulation downstream of myostatin
• Skeletal muscle biology — myoblast proliferation, differentiation, and hypertrophy models
• SAR reference — benchmarking novel myostatin-antagonist peptide analogs

Analytical Identity and purity established by HPLC-UV with MS confirmation; sequence-consistent mass verified per lot (observed ~2955 Da, calculated 2956.5). Sterility tested (USP <71>). Lot-specific certificate of analysis supplied with every unit. Research use only. Supplied as a research reference material for in-vitro and analytical laboratory use. Not a drug, food, cosmetic, or dietary supplement. Not for use in humans or animals. No dosing information is provided or implied.