IGF-1 LR3

IGF-1 LR3 (Long R3 Insulin-like Growth Factor 1)

IGF-1 LR3, or Long R3 Insulin-like Growth Factor 1, is a synthetic, modified version of the natural Insulin-like Growth Factor 1 protein. Classified as a long-acting polypeptide growth factor, this compound incorporates specific amino acid changes and an extended chain compared to the endogenous protein. It serves as a specialized research ligand for the IGF-1 receptor (IGF-1R), commonly utilized in controlled in vitro cell culture models to examine receptor binding and cellular signaling pathways.

Technical Specifications

Research Applications

IGF-1 LR3 is utilized in laboratory science as a precise tool for studying IGF-1 receptor dynamics and the resulting downstream signaling events.

Primary fields of in vitro laboratory investigation include:

• Receptor Binding Studies: Analyzing interaction affinity with the IGF-1 receptor (IGF-1R).

• Signal Transduction Research: Observing intracellular pathway activation in in vitro systems.

• Cell Proliferation Models: Implementation in controlled culture systems to study growth factor influence.

• Comparative Ligand Analysis: Studying the specific effects of various IGF-1 analogs.

• In Vitro Mechanism Investigation: Mapping cellular signaling events and receptor engagement.

Storage & Handling Guidelines

To preserve the structural integrity and stability of the lyophilized peptide, the following laboratory protocols are required:

• Lyophilized Material: Store at room temperature, ensuring the material is kept away from direct light.

• Reconstituted Material: Samples should be kept in a refrigerator.

• Long-Term Storage: The material must be stored in a freezer.

• Environmental Control: Keep the vial tightly sealed in a dry environment with a desiccant.

• Aseptic Technique: Utilize sterile methods when performing reconstitution for research measurements.

Research Use Disclaimer

Research Use Only Disclaimer: This product is developed and distributed strictly as a Research Use Only (RUO) laboratory reference chemical intended exclusively for non-clinical analytical and scientific investigation. It is not an FDA-approved drug formulation, active pharmaceutical ingredient, or dietary supplement, and is strictly prohibited for human or veterinary consumption. Kimera Chems supplies these high-purity peptides solely to authorized research facilities for scientific investigation.