KPV (Lysine-Proline-Valine)
KPV is a synthetic, acetylated tripeptide derived as the C-terminal fragment of alpha-melanocyte-stimulating hormone (α-MSH). In controlled laboratory environments, this molecule acts as a probe for investigating interactions with melanocortin receptors. Researchers utilize KPV to explore cellular signaling pathways in various models, allowing for the analysis of specific biochemical interactions without the complexities associated with larger peptide hormones or full-length protein sequences.
Technical Specifications
| Property | Specification |
| Product Name | KPV |
| Chemical Composition | Lysine-Proline-Valine (Acetylated) |
| Molecular Formula | C16H30N4O4 |
| Molecular Weight | 343.4 g/mol |
| Chemical Class | Alpha-MSH C-terminal fragment |
| Assay Purity | ≥98% (HPLC verified) |
Research Applications
KPV serves as a specialized tool for mapping melanocortin receptor signaling and evaluating the biochemical properties of short-chain peptide sequences.
Primary fields of in vitro laboratory investigation include:
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Signal Transduction Analysis: Mapping the chemical signaling events activated during peptide-receptor interaction.
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Peptide Stability Research: Examining the resistance of the tripeptide sequence to degradation when exposed to various laboratory enzymes.
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Molecular Docking Evaluation: Utilizing the peptide to validate computational models of peptide-receptor binding architecture.
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In Vitro Modeling: Studying cellular communication and surface protein interaction in simulated cellular environments.
Storage & Handling Guidelines
To maintain the integrity and research viability of the peptide, the following laboratory protocols are required:
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Lyophilized Material: Store at room temperature, ensuring the material is kept away from direct light.
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Reconstituted Material: Samples should be kept in a refrigerator.
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Long-Term Storage: The material must be stored in a freezer.
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Environmental Control: Use airtight seals to prevent the material from absorbing atmospheric moisture.
Research Use Disclaimer
Research Use Only Disclaimer: This product is developed and distributed strictly as a Research Use Only (RUO) laboratory reference chemical intended exclusively for non-clinical analytical and scientific investigation. It is not an FDA-approved drug, food, dietary supplement, or cosmetic, and is strictly prohibited for human or animal consumption. Kimera Chems supplies these high-purity peptides solely to professional laboratories and qualified scientific investigators.
| CAS Number | 67727-97-3 |
| Other Names | Lysine-Proline-Valine |
| IUPAC Name | N-acetyl-L-lysyl-L-prolyl-L-valinamide |
| Molecular Formula | C16H30N4O4 |
| Molecular Weight | 343.4 |











