Kisspeptin-10

Kisspeptin-10 (Metastin 45-54)

Kisspeptin-10 is a synthetic decapeptide representing the shortest functional sequence of the larger kisspeptin protein. A key member of the RF-amide peptide family, this compound serves as a primary research tool for investigating the Kiss1 receptor (GPR54). In controlled in vitro laboratory models, Kisspeptin-10 is utilized to map the molecular architecture of reproductive signaling within the hypothalamic-pituitary-gonadal axis and explore the dynamics of G-protein-coupled receptor (GPCR) binding.

Technical Specifications

Research Applications

Kisspeptin-10 functions as a structural probe for examining hormonal regulation pathways and GPR54-mediated signaling cascades in controlled laboratory environments.

Primary fields of in vitro laboratory investigation include:

• Receptor Binding Analysis: Measuring binding affinity and kinetics between the decapeptide and the GPR54 receptor.

• Signal Pathway Mapping: Tracking intracellular chemical signaling events initiated by receptor engagement.

• Structural Degradation Studies: Examining peptide stability and half-life within varying chemical environments.

• Neuroendocrine Modeling: Simulating and studying hypothalamic signaling dynamics.

• Molecular Docking Tests: Validating computational models of protein-peptide complex architecture.

Storage & Handling Guidelines

To maintain the stability and experimental validity of the lyophilized peptide, the following laboratory protocols are required:

• Lyophilized Material: Store at room temperature, ensuring the material is kept away from direct light.

• Reconstituted Material: Samples should be kept in a refrigerator.

• Long-Term Storage: The material must be stored in a freezer.

• Environmental Control: Keep the container tightly closed and protect from light.

• Moisture Protection: Place the container in a dry environment and utilize desiccants to prevent atmospheric moisture degradation.

Research Use Disclaimer

Research Use Only Disclaimer: This product is developed and distributed strictly as a Research Use Only (RUO) laboratory reference chemical intended exclusively for non-clinical analytical and scientific investigation. It is not an FDA-approved drug formulation, diagnostic agent, or therapeutic medication, and is strictly prohibited for human or animal consumption. Kimera Chems supplies these high-purity peptides solely to professional laboratories and verified scientific investigators.