RGPU-95 (p-Cl-Phenylpiracetam) Research Standard
RGPU-95 (p-Cl-Phenylpiracetam) is a synthetic racetam-class compound characterized by the addition of a chlorine atom to the phenylpiracetam scaffold. This structural modification is a focal point in pharmacological research, specifically investigated for how it alters the compound’s stability, lipophilicity, and pharmacological potency in in vitro models. In laboratory settings, RGPU-95 is utilized as a high-potency tool for mapping signal transmission dynamics within nerve tissue and observing cellular responses to stressors in controlled experimental environments.
Technical Specifications
| Property | Specification |
| Product Name | RGPU-95 (p-Cl-Phenylpiracetam) |
| Chemical Formula | $C_{12}H_{13}ClN_2O_2$ |
| Molecular Weight | ~238.67 g/mol |
| Chemical Class | Racetam derivative (Chlorinated) |
| Physical Appearance | Fine white powder |
| Assay Purity | $ge 99%$ (HPLC verified) |
Mechanism of Action & Research Context
The chemical modification of phenylpiracetam with a para-chlorine substituent provides a stable and robust scaffold for long-term laboratory investigations.
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Structural Stability: The chlorinated phenyl ring confers increased structural toughness, making RGPU-95 an ideal candidate for long-term in vitro experiments where compound stability over several months is required.
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Signaling Modulation: Research focuses on the compound’s interaction with neurotransmitter pathways, particularly its ability to modulate signal velocity and transduction efficiency between neurons in cultured tissue.
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Cellular Resilience: Because the compound is utilized to study cells under “pressure,” it acts as a valuable reference in experiments measuring how neural tissue maintains viability or signaling integrity when exposed to thermal or metabolic stress.
Research Applications
RGPU-95 is a specialized reference material for cognitive science and neuropharmacology.
Primary fields of in vitro laboratory investigation include:
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GABAergic Signaling: Investigating the modulation of GABA receptor activity in isolated nerve tissue models.
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Bioenergetic Stress Testing: Examining energy utilization in neural cells under low-temperature (cold stress) conditions.
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Permeability Studies: Investigating the kinetics of the compound’s movement across cellular barriers and membrane systems.
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Signal Speed Dynamics: Quantifying changes in signal propagation speed between nerve cells in controlled culture environments.
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Comparative Neuropharmacology: Utilizing the chlorinated scaffold to compare binding and activity profiles against the parent phenylpiracetam molecule.
Storage & Handling Guidelines
To maintain the chemical integrity of the material:
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Environment: Store the container in a cool, dry laboratory environment.
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Light Sensitivity: Protect from direct sunlight; store in a dark cabinet to prevent UV-induced degradation of the molecular structure.
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Container Integrity: Ensure the lid is twisted on tightly immediately after use to prevent moisture absorption.
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Handling: Use a dry scoop (for powder) or a clean, calibrated dropper (for liquid) to avoid contamination. Maintain a clean, dedicated workspace to prevent cross-contamination with other research reagents.
Research Use Disclaimer
Research Use Only Disclaimer: This product is developed and distributed strictly as a Research Use Only (RUO) laboratory reference chemical intended exclusively for non-clinical analytical and scientific investigation. It is not an FDA-approved drug, medical treatment, dietary supplement, or food ingredient, and is strictly prohibited for human or animal consumption. Kimera Chems supplies this high-purity research material solely to qualified institutions and professional investigators for authorized laboratory research.
| CAS Number | 213178-69-9 |
| Other Names | 1-Pyrrolidineacetamide, 4-(4-chlorophenyl)-2-oxo; RGPU-95 |
| IUPAC Name | 2-(2-oxo-4-(4-chlorophenyl)-pyrrolidin-1-yl)acetamide2-(2-oxo-4-(4-chlorophenyl)-pyrrolidin-1-yl)acetamide |
| Molecular Formula | C₁₂H₁₃ClN₂O₂ |
| Molecular Weight | 252.7 g/mol |
| Liquid Concentration And Solution | 20mg/ml – Solution: PEG400, DMSO |




