Author Archives: Kimerachemss

How to Evaluate Peptide Purity Documentation

Peptide purity documentation with HPLC and mass spectrometry results

Peptide purity documentation should provide more than a single percentage. A useful documentation package should help a laboratory evaluate peptide identity, chromatographic purity, batch traceability and the limitations of the analytical methods used. High-performance liquid chromatography and mass spectrometry provide different types of evidence. HPLC can describe the chromatographic profile of a sample under defined […]

What Batch-Level Testing Means for Research Chemicals

Batch-level testing for research chemicals

Batch-level testing for research chemicals connects analytical results to a specific production or testing lot. Rather than relying on a general report for a compound name, researchers can use a batch number to determine whether a Certificate of Analysis corresponds to the material being evaluated. This distinction matters because separate batches of the same compound […]

HPLC vs Mass Spectrometry for Research Compound Verification

HPLC vs mass spectrometry for research compounds

Understanding HPLC vs mass spectrometry for research compounds helps researchers distinguish between chromatographic purity information and molecular identity evidence. Although both methods appear frequently on Certificates of Analysis, they measure different properties and should not be treated as interchangeable tests. High-performance liquid chromatography, or HPLC, separates detectable components within a sample. Mass spectrometry, or MS, […]

How to Read a Research Compound COA: HPLC, MS & NMR

How to read a research compound COA with HPLC, MS and NMR data

Learning how to read a research compound COA is essential when reviewing the identity, purity and batch documentation of a laboratory material. A Certificate of Analysis should connect a specific batch to clearly reported analytical results rather than simply display a purity percentage. HPLC, mass spectrometry and NMR provide different kinds of information. No single […]